Diseases that Harm Require Therapies that Harm Less

---Sir William Osler(1849-1919)
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ISMIVS Newsletter July&August, 2023

Newsletter 2023 Jul & Aug
About Us 国际微无创医学会简介
The International Society of Minimally Invasive and Virtual Surgery (ISMIVS, previously known as International Society of Minimally Invasive and Noninvasive Medicine) was founded in July 2013 at the gala of the 1st Yangtze International Summit of Minimally Invasive and Noninvasive Medicine in Chongqing, China. ISMIVS envisions to accelerating the progress in minimally invasive and noninvasive medicine by promoting research, education, communication, and international collaboration.
国际微无创医学会(ISMIVS)是在 2013 年 7 月在中国重庆召开的第一届国际微无创医学长江高峰论坛上宣布成立的,旨在通过学术研究、教育、交流以及国际合作加快微无创医学的发展。
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The Personality in the Medical Education World 医学教育界的大人物
From the 2020 July issue of our ISMIVS Newsletter, we would like to introduce some pioneers in the field of minimally-invasive and noninvasive medicine. They are not only prestigious in their field but also willing to share their experience and ideas with younger doctors, hence making a great contribution to medical education. This issue features Prof. Tan-To Cheung, a prominent surgeon from the University of Hong Kong.
从 2020 年 7 月刊开始,国际微无创医学会将为大家介绍微无创医学领域的一些领军人物。他们不仅在各自的领域享负盛名,而且非常乐意与年轻医生分享他们的经验、理念和想法,从而为医学教育做出了巨大的贡献。本期月刊要介绍的是香港大学的临床专家张丹图教授。

Prof. Tan-To Cheung
Clinical Professor
The University of Hong Kong

Chief of Division of Hepatobiliary and Pancreatic Surgery, Queen Mary Hospital, the University of Hong Kong
President of the Hong Kong Society of Hepatobiliary and Pancreatic Surgery
Vice President of ISMIVS

Prof. Tan-To Cheung is the Chief of the Division of Hepatobiliary and Pancreatic Surgery within the Department of Surgery, Queen Mary Hospital, the University of Hong Kong, and President of the Hong Kong Society of Hepatobiliary and Pancreatic Surgery, Vice President (External Affairs) of College of Surgeons on Hong Kong and Council Member of Liver Foundation. He is currently a Clinical Professor at the University of Hong Kong.
Prof. Cheung is an experienced academic surgeon and his research interest was focused on disease and cancers in the liver, biliary tract and pancreas. He is the chairman of the Hong Kong Pancreatic Cystic Lesion Management Consensus Meeting 2022, the Hong Kong Consensus recommendation on the management of HCC 2018 and 2021, and the Asia Pacific Consensus Meeting for minimally invasive hepatectomy for primary liver cancer (Hong Kong Statement) in 2016.
Prof. Cheung is a world-renowned leading expert in the field of laparoscopic liver resection for primary liver cancer. He is the pioneer of laparoscopic liver hepatectomies in Hong Kong with good outcomes. He completed the degree of Doctor of Medicine in 2018. His thesis was the “Application on Minimally Invasive Hepatectomy for liver cancer.” He is very active and visionary in this field internationally. He was the founding member of the International Laparoscopic Liver Surgery Society and was elected as an Advisory Board Member in 2019. Chairman of Radiology Committee of International Liver Transplant Society 2019-2022.
张教授是世界知名的腹腔镜肝切除治疗原发性肝癌专家。他是香港腹腔镜肝切除术的先驱,且治疗效果良好。他在这一领域非常活跃,在国际上也很有远见。他是国际腹腔镜肝脏外科协会的创始成员,并于 2019 年当选为顾问委员会成员。国际肝脏移植学会放射学委员会主席(2019-2022)。
Prof. Cheung was a recipient of the GB Ong Travelling Fellowship Award 2013 and the James IV Travelling Fellowship Award 2017. He has authored more than 310 peer-reviewed articles and other publications and is frequently invited to lecture internationally and to present in plenary sessions. He is listed as top 1% of HKU researchers ranked by Clarivate Analytics worldwide by citations in 2021. He has mentored a large number of trainees, including post-graduate degrees and overseas academia.
张教授曾获2013年GB Ong Travelling Fellowship Award及2017年James IV Travelling Fellowship Award。他撰写了310多篇经同行评审的文章和其他出版物,并经常应邀在国际上讲学和在全体会议上发言。他被Clarivate Analytics列为2021年全球引文排名前1%的香港大学研究人员。此外,他是许多研究生和海外学者的导师。
Read his article on laparoscopic hepatectomy:
Article reference:
News 新闻
Prominent Experts Discuss the Development of "Minimally and Non-invasive Medicine" Together
On July 8th, the section "The Development of Minimally and Non-invasive Medicine" was successfully held as part of the "5th Yangtze International Summit of Minimally invasive and Non-invasive Medicine initiated, 2023 ‘One Belt and One Road’ Micro-invasive Medicine Innovation Forum".
This part was jointly chaired by Li Qilong (from Taiwan, China), Chairman of the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapeutics(APAGE), Yang Hanfeng, the Party secretary of Hospital of North Sichuan Medical College, David Cranston, President of the International Society of Minimally Invasive and Virtue Surgery (ISMIVS), Chen Chunlin, Director of Obstetrics and Gynecology at Nanfang Hospital of Southern Medical University, Zhang Lian, President of Chongqing Haifu Hospital, Vitaya Titapant, President of the Royal Thai College of Obstetricians and Gynaecologists, Chen Guoqiang, President of First People's Hospital of Foshan, Xing Ruoxi, Professor at Chongqing Medical University, and Relly Yanuari Primariawan, Council Member of the Asia-Pacific Association of Gynecologic Endoscopy and Minimally Invasive Therapeutics (APAGE).
本分论坛由亚太妇产科内视镜暨微创治疗医学会(APAGE)董事会主席李奇龙(中国台湾)、川北医学院附属医院党委书记杨汉丰、国际微无创医学会(ISMIVS)主席David Cranston、南方医科大学南方医院妇产科主任陈春林、重庆海扶医院院长张炼、泰国皇家妇产科学院院长Vitaya Titapant、佛山市第一人民医院院长陈国强、重庆医科大学教授邢若曦、亚太妇科内镜与微创治疗协会(APAGE)理事Relly Yanuari Primariawan等人共同担任主持。
A total of 10 experts shared their brilliant lectures on "The Development of Minimally and Non-invasive Medicine" and jointly explored cutting-edge technologies in the field of minimally and non-invasive medicine, lightening a path to the bright future of minimally and non-invasive medicine.

David Cranston, Past President of the International Society of Minimally Invasive and Virtue Surgery (ISMIVS) and professor at the University of Oxford, gave a special lecture titled "In the steps of William Osler and the Development of Noninvasive Medicine" Throughout the development of medicine, William Osler believed that "diseases that harm the human body require treatment methods that cause less harm to the body". Focusing ultrasound ablation technology is currently the best way to put this belief into practice, and it has been clinically proven to be a safe, effective and minimally invasive solution.
国际微无创医学会(ISMIVS)往届主席、牛津大学教授David Cranston分享“沿着威廉•奥斯勒的足迹看微无创医学的发展”的专题讲座。纵观医学发展过程,威廉•奥斯勒认为的“伤害人体的疾病需要对人体伤害更小的治疗方法”一直是医学追求的目标,而聚焦超声消融技术正是目前最好的践行者,临床上也已经证实这是一种安全、有效的微无创方案。

Chairman of the China-Australia-Asia Pacific Minimally Invasive Surgery Forum and Professor at the University of New South Wales, Felix Wong, Shares a Special Lecture on "Focused ultrasound surgery-potential new direction." He shared the practical applications of focused ultrasound thermal ablation and non-thermal mechanical ablation, as well as the future directions and prospects of HIFU treatment.

"Former President and Current Director of the European Society for Gynaecological Endoscopy (ESGE), Rudy Leon De Wilde, shared a special lecture on "Forget the Surgical Therapy in Adenomyosis." Focused ultrasound ablation therapy for adenomyosis has undergone evidence-based clinical research and multicenter prospective studies. With numerous clinical experiences, it has rapidly developed, demonstrating good safety and effectiveness comparable to minimally invasive surgery.
欧洲妇科内镜学会(ESGE)前任主席&现任总监Rudy Leon De Wilde分享“子宫腺肌症的治疗:忘掉手术”的专题讲座。针对子宫腺肌病的聚焦超声消融治疗,进行了循证临床研究,也做了多中心前瞻性研究,在诸多临床经验下得到快速发展,已经建立了良好的安全性,并且拥有不低于微创手术的有效性。

Professor Xin Shelley Wang from the Department of Symptom Research at The University of Texas MD Anderson Cancer Center shares a special lecture on the 'Utility of ePROs in Postoperative Care.' In team-based cancer care models, electronic patient-reported outcomes (ePRO) serve as a comprehensive monitoring tool for all healthcare participants, providing management and monitoring of adverse reactions, complications, functional status, and psychological state throughout the entire cancer treatment process. The ePRO system offers additional functionalities, including rapid aggregation of individual symptom items and symptom scales, quantification and standardization of self-reported data, longitudinal patient tracking surveys for long-term.
美国德克萨斯大学MD安德森癌症中心症状研究系教授Xin Shelley Wang分享“电子化患者报告结局在术后护理中的效用”的专题讲座。以团队为基础的癌症护理模式中,电子化患者报告结局(ePRO)为所有护理工作的参与者,提供对于患者在整个癌症治疗过程中的不良反应、并发症、功能状态和心理状态的全程管理化的监测。ePRO系统能提供额外的功能,包括对个人症状条目和症状量表的快速汇总、量化且标准化自诉数据,对患者纵向跟踪调查,以便进行长期趋势分析。

Chairman of the Board of Directors of the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE), Lee Chyilong, shared a special lecture on the ' the necessity of the certification in non-minimal invasive therapy'. High-Intensity Focused Ultrasound (HIFU) was first developed in Chongqing. Guided by ultrasound, the technology uses high-intensity ultrasonic waves to selectively destroy fibroid tissue within the target area without damaging surrounding normal tissues, achieving minimally invasive treatment for uterine fibroids. This advantage of HIFU makes it one of the important trends of the future minimally invasive treatments. Safety certification requires rigorous scrutiny and assessment before comprehensive conclusions can be drawn from experimental trials.
亚太妇产科内视镜暨微创治疗医学会 (APAGE)董事会主席李奇龙分享“微无创治疗技术安全认证的必要性”的专题讲座。HIFU是由重庆最先开展的,通过超声定位后,利用高强度超声波杀灭靶区内的肌瘤组织而不损伤周围正常组织,实现对子宫肌瘤的微无创治疗。HIFU的微无创优势使其成为未来微无创治疗的重要发展趋势之一。安全性认证需要经过反复的严谨的推敲及考核,才能提出试验综合结论。

Director of the Department of Obstetrics and Gynecology at Nanfang Hospital of Southern Medical University, Chen Chunlin, shared a special lecture on the ‘Minimally invasive and noninvasive technology/artificial intelligence- future vision of diagnose and treatment obstetrics and gynaecology disease’. Focused Ultrasound Ablation Surgery (FUAS) can eliminate periodic pain associated with adenomyosis. By ablating the thickened lesions in the myometrium and reducing the lesion area of endometriosis, ectopic endometrial function is removed. Consequently, the uterine environment for conception is improved and fertility is promoted. Additionally, the lecture also explores the integration of minimally invasive surgeries such as intervention and laparoscopy with artificial intelligence.
Chairman of Suining Central Hospital Medical Group, Chen Yongjun, shared a special lecture on 'Review and outlook: progress in the field of endoscopy and future of minimally invasive and noninvasive medicine.' The first generation of surgical procedures involved open surgery, followed by the second generation which introduced minimally invasive surgery. The third generation of surgical procedures involves super minimally invasive surgery, or even non-invasive surgery, such as high-intensity focused ultrasound. Analyzing the trends of change in medicine from the perspective of historical evolution, the lecture explores the future prospects of minimally invasive surgery.

Founder and Chairman of the Focused Ultrasound Foundation, Neal F. Kassell, shared a special lecture on "'Curing with sound" Revered as a "game-changer", focused ultrasound therapy is a highly disruptive non-invasive treatment technology. It has transformed the paradigm of disease treatment and holds the potential to become a revolutionary diagnostic tool, much like magnetic resonance imaging (MRI). There is ample scientific evidence indicating the effectiveness of focused ultrasound therapy. Every year, hundreds of peer-reviewed papers are published, showcasing the benefits of this technology, with papers containing clinical trial data appearing in top medical journals such as the New England Journal of Medicine and The Lancet.
美国聚焦超声基金会创始人和主席Neal F.Kassell分享“‘声’的疗愈之道”的专题讲座。被誉为“改变医学”的聚焦超声是一项极具颠覆性的新型无创治疗技术。它改变了疾病治疗范式,有望像核磁共振(MRI)一样,成为诊断疾病的革命性技术。有充足的科学依据表明,超声聚焦疗法行之有效。每年都有千百篇发表在同行评审期刊上的论文论证这项技术的益处,含有临床试验数据的论文见于《新英格兰医学期刊》和《柳叶刀》等顶级医学期刊中。
Virginia University neurosurgeon Dr. Shayan Moosa shared a lecture on "clinical applications of focused ultrasound in the brain" The lecture introduces the clinical applications of focused ultrasound therapy in treating brain disorders.
弗吉尼亚大学的神经外科医生 Shayan Moosa 分享“聚焦超声治疗脑部疾病的临床应用”的讲题讲座。介绍了聚焦超声在脑部疾病上的临床应用。
Associate Chief Physician/Chief Physician of the Department of Obstetrics and Gynecology at Peking Union Medical College Hospital, Yu Xin, shared a special lecture on "A surgeon’s perspective on focused ultrasound therapy." The lecture emphasizes the importance of selecting treatment methods that maximize benefits and minimize harm. The best choice is the one that both doctors and patients agree upon. There is no single best method; there will always be room for improvement. It is not necessary to pursue or adhere to a specific approach. Every technique has its advantages and disadvantages, and it is important to complement each other's strengths and weaknesses.
Notice 通知
The 23rd APAGE Annual Congress

The 23rd APAGE Annual Congress will be held on October 26-28, 2023, in Singapore, please kindly save the date and see you there!
APAGE 第 23 届年会将于 2023 年 10 月 26 日 至 28 日在新加坡举行,欢迎大家参与!
More Info 更多信息:
Registration 报名资讯:

HIFU Special Issue 高强度聚焦超声特刊

We are delighted to announce that the International Journal of Hyperthermia, the HIFU Special Issue (i.e. Volume 38, 2021), which was partially supported by ISMIVS, was officially released in September. The Special Issue includes 15 articles written and reviewed by world-renowned scholars and pioneers in minimally invasive and noninvasive medicine, elaborating on the status and prospects of the clinical applications of high intensity focused ultrasound on tumours that occurred in specific organs. We'll share the 15 articles included in the upcoming newsletters, stay tuned!
The aim is to investigate the feasibility, efficacy and safety of ultrasound-guided high-intensity focused ultrasound (HIFU) ablation for treating the broad ligament uterine fibroid (BLUF).
A total of 236 patients with symptomatic uterine fibroids were enrolled and treated with JC200 extracorporeal ultrasound-guided HIFU under conscious sedation between January 2017 and December 2018. The patients’ mean age was 38.6 ± 6.3 years.
2017 年 1 月至 2018 年 12 月期间,共有 236 例有症状子宫肌瘤患者入组,并在静脉镇静镇痛下接受 JC200 体外超声引导 HIFU 治疗。患者平均年龄为 38.6 ± 6.3 岁。
Ultrasound-guided HIFU ablation in the patients was technically successful with one session of treatment. The mean longest diameter of BLUFs was 6.2 ± 2.3 cm. The mean NPV ratio of fibroids was 84.08%± 9.4%. There were no severe adverse events or complications associated with the treatment. That shows ultrasound-guided high-intensity focused ultrasound ablation is feasible, effective, and safe for treating broad ligament fibroids.
超声引导下的 HIFU 消融术在技术上通过一次治疗取得了成功。 BLUF 的平均最长直径为 6.2±2.3 cm。 肌瘤的平均消融率为 84.08% ± 9.4%。 没有与治疗相关的严重不良事件和并发症。 这表明超声引导下高强度聚焦超声消融治疗阔韧带肌瘤是可行、有效、安全的。
Read More >
Tech Update in Gynaecological Endoscopy 妇科腔镜技术最新进展
The impact of laparoscopic gynaecological surgery training on the technicity index of a developing country centre
The author from Brazil published a paper to compare laparoscopic gynaecological surgery training between a developed country’s reference centre (host centre) and a public reference service in a developing country (home centre), and use the technicity index (TI) to compare outcomes and to determine the impact of laparoscopic gynaecological surgery fellowship training on the home centre’s TI.
The analysis included 366 hysterectomies performed at the host centre (CHU – Estaing) between January and December 2017, and 663 hysterectomies performed at the home centre (Botucatu Medical School Hospital/UNESP) between January 2015 and October 2017. 这项分析包括 2017 年 1 月至 12 月在东道主中心(CHU - Estaing)进行的 366 例子宫切除术,以及2015年1月至2017 年 10 月在家庭中心(Botucatu Medical School Hospital/UNESP)进行的 663 例子宫切除术。
Taken together, their results demonstrate that access to high-quality laparoscopic training opportunities in highly experienced reference centres can have substantial benefits. It fosters the professional growth of individual surgeons, promotes high standards and best practices, and favours the structuring and development of new surgical care and training centres in the recipients’ communities, especially in developing countries. Such was the case of the experience described herein, which allowed the home centre to increase their TI based on laparoscopic procedures from 6 to 22% over a period of four years.
综上所述,他们的结果表明,在经验丰富的基准中心获得高质量的腹腔镜培训机会可以带来实质性的好处。它促进了个体外科医生的专业成长,促进了高标准和最佳实践,并有利于在接受者社区,特别是在发展中国家建立和发展新的外科护理和培训中心。这就是本文所描述的经验,它允许家庭中心在四年的时间内将基于腹腔镜手术的 TI 从6% 增加到 22%。
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